Twitterrific for Mac

Twitterrific is also available for iPad and iPhone

Small Desktop Footprint -

Designed to let you view as much or little information as you desire.
Growl Support -

Harness the power of Growl to change the way new tweets are shown on the screen.
Auto Refreshing -

User defined intervals let you decide how often Twitterrific displays new tweets.
Applescript Support -

Filter tweets, add custom behaviors & more with the power of Applescript.
Audio Notifications -

Twitterrific alerts you to new tweets with a host of customizable, friendly bird calls.
Much More! -

Dock notifications, explore settings, hotkey commands and more.